Everything You Need to Know About Bedwetting in Children

Desmopressin for Bedwetting (Enuresis)

Bedwetting is common in children, especially between the ages of 5 and 16. Although it can be distressing, it is usually harmless and often resolves on its own over time. There are several ways to treat bedwetting. One commonly used medication is desmopressin. Researchers have recently studied how effective this medication is.

What does desmopressin do?

Desmopressin reduces the amount of urine the body produces at night. This can help a child wet the bed less often.

Does it work?

Research involving more than 8,000 children shows that:

Children who use desmopressin have, on average, almost two extra dry nights per week compared with children who receive a placebo (a dummy medication).

About 3 out of 10 children temporarily stop bedwetting while using desmopressin.

Once the medication is stopped, bedwetting often returns.

Is desmopressin better than a bedwetting alarm?

No. Research shows that desmopressin is not more effective than a bedwetting alarm (a device that sounds when the first drops of urine are detected). In fact:

A bedwetting alarm often has a longer-lasting effect.

Desmopressin usually does not add extra benefit if a child is already using a bedwetting alarm.

A bedwetting alarm may help when used together with desmopressin.

Side effects
Some children may experience side effects, such as:
headache
dizziness
stomach pain
mood changes

A rare but important side effect is a disturbance of the body’s salt balance (hyponatraemia). For this reason, it is important to use desmopressin exactly as prescribed and to limit fluid intake in the evening.

What is the best advice?

According to the guideline for bedwetting:

Start with explanation and reassurance – many children outgrow bedwetting naturally.

Behavioural advice, such as regular toilet visits and spreading fluid intake throughout the day.

Use a bedwetting alarm if needed.

Use desmopressin only in special situations, such as sleepovers, school camps, or holidays.

In summary

Bedwetting can be stressful for both children and parents, but it is important to know that effective treatments are available and that there is no need to rush. Together with your family doctor, you can decide what approach best suits your child and your situation.

Do you have questions or would you like to discuss this further?
You can make an appointment online.
You can also visit Charco for more information about bedwetting alarms:
https://www.charco.be/nl/